目的;这项研究的目的是通过将机器学习应用于多模式MRI特征，将神经胶质肿瘤分为II，III和IV类别，与体积分析相比。方法;我们回顾性地研究了57例在3T MRI上获取的T2加权，T2加权，Flair图像和ADC MAP的胶质瘤患者。使用ITK-SNAP开源工具的半小局分割，将肿瘤分割为增强和非增强部分，肿瘤坏死，囊肿和水肿。我们测量了总肿瘤量，增强的非肿瘤，水肿，坏死体积以及与总肿瘤量的比率。对培训载体机（SVM）分类器和人工神经网络（ANN）进行了标记的数据，旨在回答感兴趣的问题。通过ROC分析计算预测的特异性，灵敏度和AUC。使用Kruskall Wallis评估了组之间连续度量的差异，并进行了事后DUNN校正以进行多次比较。结果;当我们比较组之间的体积比时，IV级和II-III级神经胶质肿瘤之间的统计学显着差异。 IV级神经胶质肿瘤的水肿和肿瘤坏死比率高于II和III级。体积比分析无法成功区分II和III级肿瘤。但是，SVM和ANN以高达98％和96％的精度正确分类了每个组。结论;在临床环境中，可以将机器学习方法应用于MRI特征，以无创，更容易地对脑肿瘤进行分类。

Advances in reinforcement learning have led to its successful application in complex tasks with continuous state and action spaces. Despite these advances in practice, most theoretical work pertains to finite state and action spaces. We propose building a theoretical understanding of continuous state and action spaces by employing a geometric lens. Central to our work is the idea that the transition dynamics induce a low dimensional manifold of reachable states embedded in the high-dimensional nominal state space. We prove that, under certain conditions, the dimensionality of this manifold is at most the dimensionality of the action space plus one. This is the first result of its kind, linking the geometry of the state space to the dimensionality of the action space. We empirically corroborate this upper bound for four MuJoCo environments. We further demonstrate the applicability of our result by learning a policy in this low dimensional representation. To do so we introduce an algorithm that learns a mapping to a low dimensional representation, as a narrow hidden layer of a deep neural network, in tandem with the policy using DDPG. Our experiments show that a policy learnt this way perform on par or better for four MuJoCo control suite tasks.

Hierarchical Reinforcement Learning (HRL) algorithms have been demonstrated to perform well on high-dimensional decision making and robotic control tasks. However, because they solely optimize for rewards, the agent tends to search the same space redundantly. This problem reduces the speed of learning and achieved reward. In this work, we present an Off-Policy HRL algorithm that maximizes entropy for efficient exploration. The algorithm learns a temporally abstracted low-level policy and is able to explore broadly through the addition of entropy to the high-level. The novelty of this work is the theoretical motivation of adding entropy to the RL objective in the HRL setting. We empirically show that the entropy can be added to both levels if the Kullback-Leibler (KL) divergence between consecutive updates of the low-level policy is sufficiently small. We performed an ablative study to analyze the effects of entropy on hierarchy, in which adding entropy to high-level emerged as the most desirable configuration. Furthermore, a higher temperature in the low-level leads to Q-value overestimation and increases the stochasticity of the environment that the high-level operates on, making learning more challenging. Our method, SHIRO, surpasses state-of-the-art performance on a range of simulated robotic control benchmark tasks and requires minimal tuning.

Instruction tuning enables pretrained language models to perform new tasks from inference-time natural language descriptions. These approaches rely on vast amounts of human supervision in the form of crowdsourced datasets or user interactions. In this work, we introduce Unnatural Instructions: a large dataset of creative and diverse instructions, collected with virtually no human labor. We collect 64,000 examples by prompting a language model with three seed examples of instructions and eliciting a fourth. This set is then expanded by prompting the model to rephrase each instruction, creating a total of approximately 240,000 examples of instructions, inputs, and outputs. Experiments show that despite containing a fair amount of noise, training on Unnatural Instructions rivals the effectiveness of training on open-source manually-curated datasets, surpassing the performance of models such as T0++ and Tk-Instruct across various benchmarks. These results demonstrate the potential of model-generated data as a cost-effective alternative to crowdsourcing for dataset expansion and diversification.

Reranking methods in machine translation aim to close the gap between common evaluation metrics (e.g. BLEU) and maximum likelihood learning and decoding algorithms. Prior works address this challenge by training models to rerank beam search candidates according to their predicted BLEU scores, building upon large models pretrained on massive monolingual corpora -- a privilege that was never made available to the baseline translation model. In this work, we examine a simple approach for training rerankers to predict translation candidates' BLEU scores without introducing additional data or parameters. Our approach can be used as a clean baseline, decoupled from external factors, for future research in this area.

Multilingual machine translation models can benefit from synergy between different language pairs, but also suffer from interference. While there is a growing number of sophisticated methods that aim to eliminate interference, our understanding of interference as a phenomenon is still limited. This work identifies the main factors that contribute to interference in multilingual machine translation. Through systematic experimentation, we find that interference (or synergy) are primarily determined by model size, data size, and the proportion of each language pair within the total dataset. We observe that substantial interference occurs mainly when the model is very small with respect to the available training data, and that using standard transformer configurations with less than one billion parameters largely alleviates interference and promotes synergy. Moreover, we show that tuning the sampling temperature to control the proportion of each language pair in the data is key to balancing the amount of interference between low and high resource language pairs effectively, and can lead to superior performance overall.

A digital twin is defined as a virtual representation of a physical asset enabled through data and simulators for real-time prediction, optimization, monitoring, controlling, and improved decision-making. Unfortunately, the term remains vague and says little about its capability. Recently, the concept of capability level has been introduced to address this issue. Based on its capability, the concept states that a digital twin can be categorized on a scale from zero to five, referred to as standalone, descriptive, diagnostic, predictive, prescriptive, and autonomous, respectively. The current work introduces the concept in the context of the built environment. It demonstrates the concept by using a modern house as a use case. The house is equipped with an array of sensors that collect timeseries data regarding the internal state of the house. Together with physics-based and data-driven models, these data are used to develop digital twins at different capability levels demonstrated in virtual reality. The work, in addition to presenting a blueprint for developing digital twins, also provided future research directions to enhance the technology.

A fundamental characteristic common to both human vision and natural language is their compositional nature. Yet, despite the performance gains contributed by large vision and language pretraining, we find that - across 6 architectures trained with 4 algorithms on massive datasets - they exhibit little compositionality. To arrive at this conclusion, we introduce a new compositionality evaluation benchmark CREPE which measures two important aspects of compositionality identified by cognitive science literature: systematicity and productivity. To measure systematicity, CREPE consists of three test datasets. The three test sets are designed to test models trained on three of the popular training datasets: CC-12M, YFCC-15M, and LAION-400M. They contain 385K, 385K, and 373K image-text pairs and 237K, 210K, and 178K hard negative captions. To test productivity, CREPE contains 17K image-text pairs with nine different complexities plus 246K hard negative captions with atomic, swapping, and negation foils. The datasets are generated by repurposing the Visual Genome scene graphs and region descriptions and applying handcrafted templates and GPT-3. For systematicity, we find that model performance decreases consistently when novel compositions dominate the retrieval set, with Recall@1 dropping by up to 8%. For productivity, models' retrieval success decays as complexity increases, frequently nearing random chance at high complexity. These results hold regardless of model and training dataset size.

Large language models (LLMs) have been shown to be able to perform new tasks based on a few demonstrations or natural language instructions. While these capabilities have led to widespread adoption, most LLMs are developed by resource-rich organizations and are frequently kept from the public. As a step towards democratizing this powerful technology, we present BLOOM, a 176B-parameter open-access language model designed and built thanks to a collaboration of hundreds of researchers. BLOOM is a decoder-only Transformer language model that was trained on the ROOTS corpus, a dataset comprising hundreds of sources in 46 natural and 13 programming languages (59 in total). We find that BLOOM achieves competitive performance on a wide variety of benchmarks, with stronger results after undergoing multitask prompted finetuning. To facilitate future research and applications using LLMs, we publicly release our models and code under the Responsible AI License.

Assigning qualified, unbiased and interested reviewers to paper submissions is vital for maintaining the integrity and quality of the academic publishing system and providing valuable reviews to authors. However, matching thousands of submissions with thousands of potential reviewers within a limited time is a daunting challenge for a conference program committee. Prior efforts based on topic modeling have suffered from losing the specific context that help define the topics in a publication or submission abstract. Moreover, in some cases, topics identified are difficult to interpret. We propose an approach that learns from each abstract published by a potential reviewer the topics studied and the explicit context in which the reviewer studied the topics. Furthermore, we contribute a new dataset for evaluating reviewer matching systems. Our experiments show a significant, consistent improvement in precision when compared with the existing methods. We also use examples to demonstrate why our recommendations are more explainable. The new approach has been deployed successfully at top-tier conferences in the last two years.